Naldemedine - Shionogi

Drug Profile

Naldemedine - Shionogi

Alternative Names: Rizmoic; S-297995; Symproic

Latest Information Update: 11 Oct 2018

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At a glance

  • Originator Shionogi
  • Developer Purdue Pharma; Shionogi
  • Class Small molecules
  • Mechanism of Action Opioid mu receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Constipation

Most Recent Events

  • 12 Sep 2018 Pharmacodynamics data from a preclinical study in Opioid induced nausea and vomiting (OINV) presented at the 17th World Congress on Pain (WCP-2018)
  • 12 Jul 2018 Naldemedine - Shionogi is available for licensing as of 09 Jul 2018.
  • 09 Jul 2018 Shionogi and Purdue Pharma terminate the agreement for joint commercialisation of naldemedine in USA
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