VB 201
Alternative Names: CI-201; VB-201Latest Information Update: 07 Jun 2024
At a glance
- Originator VBL Therapeutics
- Developer Notable Labs
- Class Anti-inflammatories; Antifibrotics; Hepatoprotectants; Phospholipids; Small molecules
- Mechanism of Action CD14 antigen inhibitors; Cell movement inhibitors; Interleukin 12 subunit p40 inhibitors; Phospholipid modulators; Toll-like receptor 2 antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase II Atherosclerosis; COVID 2019 infections
- No development reported Hepatic fibrosis; Inflammatory bowel diseases; Multiple sclerosis; Non-alcoholic fatty liver disease; Renal fibrosis; Rheumatoid arthritis
- Discontinued Plaque psoriasis; Ulcerative colitis
Most Recent Events
- 25 Oct 2022 VBL Therapeutics completes a phase II trial for COVID-2019 infections in Israel (PO) (NCT04733833)
- 28 Sep 2022 No recent reports of development identified for preclinical development in Renal-fibrosis in Israel (PO, Capsule)
- 25 Jun 2021 University of California plans a phase I/II VITAL HIV trial in Inflammation (in treated HIV) in USA (PO, Tablet) in July 2022 (NCT04939311)