VB 201

Drug Profile

VB 201

Alternative Names: CI-201; VB-201

Latest Information Update: 04 Sep 2018

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At a glance

  • Originator VBL Therapeutics
  • Class Anti-inflammatories; Antifibrotics; Hepatoprotectants; Phospholipids; Small molecules
  • Mechanism of Action CD14 antigen inhibitors; Cell movement inhibitors; Interleukin 12 subunit p40 inhibitors; Phospholipid modulators; Toll like receptor 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Atherosclerosis
  • Preclinical Hepatic fibrosis; Non-alcoholic fatty liver disease; Renal fibrosis
  • No development reported Inflammatory bowel diseases; Multiple sclerosis; Rheumatoid arthritis
  • Discontinued Plaque psoriasis; Ulcerative colitis

Most Recent Events

  • 30 Aug 2018 VBL Therapeutics has patent protection for VBL 201 and lecinoxoid programmes in USA
  • 30 Aug 2018 Preclinical trials in Renal fibrosis in Israel (PO) before August 2018
  • 03 Apr 2017 Pharmacodynamics data from a post-hoc analysis of phase II trials released by VBL Therapeutics
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