Research programme: cyclophilin inhibitors - ContraVir Pharmaceuticals

Drug Profile

Research programme: cyclophilin inhibitors - ContraVir Pharmaceuticals

Alternative Names: 440-02; CPI-431-32

Latest Information Update: 28 Sep 2018

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At a glance

  • Originator Isotechnika Pharma
  • Developer Aurinia Pharmaceuticals; ContraVir Pharmaceuticals
  • Class Antivirals; Ciclosporins; Cyclic peptides; Hepatoprotectants; Neuroprotectants
  • Mechanism of Action Cyclophilin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Hepatitis B; Neurological disorders; Reperfusion injury

Most Recent Events

  • 28 Sep 2018 Discontinued - Preclinical for Hepatitis B in Japan (PO)
  • 28 Sep 2018 Discontinued - Preclinical for Hepatitis B in USA (PO)
  • 17 Oct 2017 ContraVir Pharmaceuticals entered into collaboration with the Li Ka Shing Institute of Virology at University of Alberta to evaluate CRV 431 for Hepatitis B treatment
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