Valbenazine - Neurocrine Biosciences

Drug Profile

Valbenazine - Neurocrine Biosciences

Alternative Names: INGREZZA; MT 5199; NBI-98854; Valbenazine-tosylate; VMAT2-inhibtor-Neurocrine-Biosciences

Latest Information Update: 13 Nov 2018

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At a glance

  • Originator Neurocrine Biosciences
  • Developer Mitsubishi Tanabe Pharma Corporation; Neurocrine Biosciences
  • Class 3-ring heterocyclic compounds; Amino acids; Neuropsychotherapeutics; Small molecules
  • Mechanism of Action Vesicular monoamine transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gilles de la Tourette's syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Drug-induced dyskinesia
  • Phase II Gilles de la Tourette's syndrome
  • Discontinued Huntington's disease; Schizophrenia

Most Recent Events

  • 01 Jun 2018 Neurocrine initiatesan open-label extension T-Force GOLD Plus trial for Gilles de la Tourette's syndrome (In adolescents, In children) in USA
  • 08 May 2018 Additional interim efficacy data from the phase III KINECT-4 trial in Drug-induced dyskinesia released by Neurocrine Biosciences
  • 25 Apr 2018 Additional long-term efficacy data from the phase III KINETIC 3 trial in Drug-induced dyskinesia presented at the 70th Annual Meeting of the American Academy of Neurology (AAN-2018)
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