Valbenazine - Neurocrine Biosciences
Alternative Names: DYSVAL; DYSVAL capsules 40mg; INGREZZA; INGREZZA SPRINKLE; MT 5199; NBI-98854; REMLEAS; Valbenazine-tosylate; VMAT2-inhibtor-Neurocrine-BiosciencesLatest Information Update: 07 Oct 2024
At a glance
- Originator Neurocrine Biosciences
- Developer Mitsubishi Tanabe Pharma Corporation; Neurocrine Biosciences
- Class 3-ring heterocyclic compounds; Amino acids; Antipsychotics; Neuropsychotherapeutics; Small molecules
- Mechanism of Action Vesicular monoamine transporter 2 inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Chorea; Tardive dyskinesia
- Phase III Cerebral palsy; Schizophrenia
- Phase II Gilles de la Tourette's syndrome
Most Recent Events
- 30 Sep 2024 Efficacy data from the phase III KINECT-HD2 trial in Chorea released by Neurocrine Biosciences
- 21 May 2024 The US FDA label for valbenazine has boxed warning for depression and suicidal ideation and behavior in patients with huntington’s disease
- 30 Apr 2024 Registered for Chorea in USA (PO)