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Rapastinel - AbbVie

Drug Profile

Rapastinel - AbbVie

Alternative Names: BV-102; GLYX-13; GLYX-13-peptide; GLYX-13-trifluoroacetate; TPPT-amide; TPPT-amide-trifluoroacetate

Latest Information Update: 05 Jan 2023

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At a glance

  • Originator Northwestern University
  • Developer Allergan; Naurex
  • Class Amides; Analgesics; Antidepressants; Neuropsychotherapeutics; Oligopeptides; Small molecules
  • Mechanism of Action NR2B N-Methyl-D-Aspartate receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Bipolar depression; Major depressive disorder; Neuropathic pain

Most Recent Events

  • 29 Sep 2022 Gate Neurosciences acquires Rapastinel from AbbVie
  • 08 May 2020 Allergan has been acquired and merged into AbbVie
  • 29 Jul 2019 Discontinued - Phase-III for Major depressive disorder (Adjunctive treatment, Prevention of relapse) in USA (IV) (NCT03668600)
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