Tepotinib - Merck KGaA

Drug Profile

Tepotinib - Merck KGaA

Alternative Names: EMD-1214063; MSC-2156119; MSC-2156119J

Latest Information Update: 20 Jul 2018

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At a glance

  • Originator EMD Serono; Merck KGaA; Merck Serono
  • Class Antineoplastics; Nitriles; Piperidines; Pyridazines; Pyrimidines; Small molecules
  • Mechanism of Action Proto oncogene protein c met inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatocellular carcinoma; Non-small cell lung cancer
  • Phase I Solid tumours

Most Recent Events

  • 13 Jun 2018 Merck KGaA and EMD Serono initiates a phase I trial in USA (PO) (NCT03546608)
  • 08 Jun 2018 Merck KGaA and EMD Serono plans a phase I trial in USA in 2018 (PO) (NCT03546608)
  • 04 Jun 2018 Efficacy and adverse events data from the phase II VISION trial in Non-small cell lung cancer presented at the American Society of Clinical Oncology (ASCO-2018)
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