Ertugliflozin - Merck/Pfizer

Drug Profile

Ertugliflozin - Merck/Pfizer

Alternative Names: MK-8835; PF-04971729; PF-4971729; STEGLATRO

Latest Information Update: 31 Jan 2018

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At a glance

  • Originator Pfizer
  • Developer Merck & Co; Pfizer
  • Class Antihyperglycaemics; Chlorobenzenes; Glycosides; Heterocyclic bicyclo compounds; Phenyl ethers; Small molecules
  • Mechanism of Action Sodium-glucose transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Registered Type 2 diabetes mellitus
  • Discontinued Hypertension

Most Recent Events

  • 31 Jan 2018 Merck Sharp & Dohme Corp. plans the ERADICATE-HF phase II trial for Type 2 diabetes mellitus and Heart failure in March 201(NCT03416270)
  • 25 Jan 2018 The Committee for Medicinal Products for Human Use (CHMP) recommends approval of ertugliflozin for Type-2 diabetes mellitus in European Union
  • 22 Dec 2017 Merck completes the phase III VERTIS trial in Type-2 diabetes mellitus (Adjunctive therapy) in South Korea (PO) (NCT02630706)
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