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Research programme: cancer metabolism therapeutics - Agios/Celgene

Drug Profile

Research programme: cancer metabolism therapeutics - Agios/Celgene

Alternative Names: AGI-14100; Glutaminase - Agios/Celgene; isocitrate dehydrogenase inhibitors - Agios/Celgene

Latest Information Update: 20 Mar 2018

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At a glance

  • Originator Agios Pharmaceuticals
  • Class Small molecules
  • Mechanism of Action Glutamine inhibitors; Isocitrate dehydrogenase 1 inhibitors; Isocitrate dehydrogenase 2 inhibitors; Phosphofructokinase modulators; Pyruvate kinase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Acute myeloid leukaemia; Brain cancer; Cancer; Myelodysplastic syndromes

Most Recent Events

  • 14 Feb 2018 Agios Pharmaceuticals has issued patents and pending patents covering IDH mutant product candidates in countries worldwide
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Acute-myeloid-leukaemia in USA (PO)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Myelodysplastic-syndromes in USA (PO)
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