Vadadustat - Akebia Therapeutics

Drug Profile

Vadadustat - Akebia Therapeutics

Alternative Names: AKB-6548; MT 6548; PG-1016548

Latest Information Update: 07 May 2018

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At a glance

  • Originator Procter & Gamble
  • Developer Akebia Therapeutics; Mitsubishi Tanabe Pharma Corporation
  • Class Antianaemics; Chlorophenols; Pyridines; Small molecules
  • Mechanism of Action Hypoxia-inducible factor-proline dioxygenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Anaemia

Most Recent Events

  • 11 Apr 2018 Akebia Therapeutics terminates the FO2RWARD phase II trial in Anaemia in USA, to revise study design (NCT03140722)
  • 14 Mar 2018 Phase-III clinical trials in Anaemia in Japan (PO) (NCT03461146)
  • 12 Mar 2018 Akebia Therapeutics has issued or pending patents for processes for manufacturing vadadustat, dosing regimens, formulations, and various other aspects relating to the treatment of anaemia using vadadustat in countries worldwide
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