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Selisistat

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Drug Profile

Selisistat

Alternative Names: EX-527; SEN 0014196; SEN196

Latest Information Update: 28 Jul 2024

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At a glance

  • Originator Elixir Pharmaceuticals
  • Developer AOP Orphan Pharmaceuticals AG; Siena Biotech
  • Class Amides; Antineoplastics; Carbazoles; Neuroprotectants; Small molecules
  • Mechanism of Action SIRT1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Huntington's disease
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Huntington's disease

Most Recent Events

  • 28 Jul 2024 No recent reports of development identified for phase-I development in Huntington's-disease in USA (PO, Tablet)
  • 21 Jul 2022 Selisistat is still in phase I/II trials for Huntington's disease in European Union and USA (AOP Orphan Pharmaceuticals pipeline, July 2022)
  • 21 Jul 2022 No development reported - Phase-II for Huntington's disease in Austria (PO)

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