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Research programme: proteostasis regulators - Kineta

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Drug Profile

Research programme: proteostasis regulators - Kineta

Alternative Names: PTI-130; PTI-C1811; PTI-P271

Latest Information Update: 29 Feb 2024

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At a glance

  • Originator Proteostasis Therapeutics
  • Developer Biogen; Cystic Fibrosis Foundation Therapeutics; Harvard Medical School; Kineta
  • Class Small molecules
  • Mechanism of Action Alpha-synuclein inhibitors; Cystic fibrosis transmembrane conductance regulator stimulants; Protein folding modulators; Protein modulators; USP14 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Chronic obstructive pulmonary disease; Cystic fibrosis; Inflammation; Metabolic disorders; Neurodegenerative disorders; Parkinson's disease

Most Recent Events

  • 31 Dec 2023 proteostasis regulators research programme licensed to Fair Therapeutics
  • 19 Dec 2022 Yumanity Therapeutics has merged with Kineta to form Kineta
  • 28 Aug 2020 No recent reports of development identified for preclinical development in Cystic-fibrosis in USA (PO)

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