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Volanesorsen - Ionis Pharmaceuticals

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Drug Profile

Volanesorsen - Ionis Pharmaceuticals

Alternative Names: IONIS-304801; IONIS-APOCIII; IONIS-APOCIIIRx; ISIS-304801; ISIS-APOCIII; ISIS-APOCIII-Rx; Volanesorsen; Volanesorsen sodium; WAYLIVRA

Latest Information Update: 05 Dec 2022

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer Akcea Therapeutics; Ionis Pharmaceuticals
  • Class Antihyperlipidaemics; Antisense oligonucleotides; Antisense RNA; Cardiovascular therapies
  • Mechanism of Action Apolipoprotein C-III inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hyperlipoproteinaemia; Lipodystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Familial partial lipodystrophy; Hyperlipoproteinaemia type I
  • Phase III Hypertriglyceridaemia

Most Recent Events

  • 01 Dec 2022 Launched for Familial partial lipodystrophy in Brazil (SC)
  • 01 Dec 2022 Registered for Familial partial lipodystrophy in Brazil (SC) - first global approval
  • 24 Feb 2022 Preregistration for Familial partial lipodystrophy in Brazil (SC)

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