Research programme: histone deacetylase-6 protein inhibitors - Karus Therapeutics

Drug Profile

Research programme: histone deacetylase-6 protein inhibitors - Karus Therapeutics

Alternative Names: HDAC-6 inhibitors - Karus; HDAC6i - Karus; KAR 2581; KAR 3000; KAR 3166

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Karus Therapeutics
  • Developer Karus Therapeutics; Kings College London; Queen Elizabeth Hospital
  • Class Antineoplastics; Depsipeptides; Small molecules
  • Mechanism of Action HDAC6 protein inhibitors; Histone deacetylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Haematological malignancies; Solid tumours
  • No development reported Inflammation; Psoriasis; Rheumatoid arthritis; Transplant rejection

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for research development in Inflammation in United Kingdom (PO)
  • 04 Nov 2017 No recent reports of development identified for research development in Psoriasis in United Kingdom (PO)
  • 04 Nov 2017 No recent reports of development identified for research development in Rheumatoid-arthritis in United Kingdom (PO)
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