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HDM-SPIRE

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Drug Profile

HDM-SPIRE

Alternative Names: Antiallergy vaccine house dust mite - NIOX; House dust mite allergy immunotherapy - NIOX; House dust mite allergy vaccine - NIOX; House dust mite SPIRE; ToleroMune HDM; ToleroMune house dust mite

Latest Information Update: 29 Jun 2023

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At a glance

  • Originator Circassia
  • Developer NIOX
  • Class Allergens; Allergy immunotherapies; Antiallergics; Peptide vaccines; Peptides
  • Mechanism of Action Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Allergic rhinoconjunctivitis

Most Recent Events

  • 13 Apr 2017 Circassia completes a phase II trial in Allergic rhinoconjunctivitis in USA, Canada, France, Germany, Italy, Latvia, Lithuania, Netherlands, South Africa, Spain (NCT02150343)
  • 28 Jul 2015 Phase-II development is ongoing in Canada, France, Germany, Italy, Netherlands, South Africa, Spain and USA
  • 01 Sep 2014 Phase-II clinical trials in Allergic rhinoconjunctivitis in USA, Germany, Italy and the Netherlands (Intradermal) (NCT02150343)

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