Research programme: immunomodulatory recombinant fusion proteins - Compugen

Drug Profile

Research programme: immunomodulatory recombinant fusion proteins - Compugen

Alternative Names: BAY 1905254; BAY 1905254/ILDR2; CGEN 15001 based protein therapeutics; CGEN 15001T based protein therapeutics; CGEN 15021 based protein therapeutics; CGEN 15022 based protein therapeutics; CGEN 15031 based protein therapeutics; CGEN 15051 based protein therapeutics; CGEN 15092 based protein therapeutics; CGEN-15029; CGEN-15029 based protein therapeutics; CGEN-15029/PVRIG; CGEN-15029/TIGIT; CGEN-15052 based protein therapeutics; CGEN-15091 based protein therapeutics; COM 701; COM701/PVRIG

Latest Information Update: 27 Jul 2018

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At a glance

  • Originator Compugen
  • Class Anti-inflammatories; Antihyperglycaemics; Antineoplastics; Antirheumatics; Monoclonal antibodies; Recombinant fusion proteins
  • Mechanism of Action CD28 antigen modulators; CD80 antigen modulators; Immunomodulators; Macrophage modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; Cancer; Multiple sclerosis; Rheumatoid arthritis; Type 1 diabetes mellitus

Most Recent Events

  • 27 Jul 2018 The US FDA approves IND application for a phase I trial of COM 701 for Solid tumours in USA
  • 02 Jul 2018 The US FDA approves IND application for a phase I trial of BAY 1905254 for Solid tumours
  • 21 Apr 2018 Pharmacodynamics data from a preclinical study in Cancer presented at the 109th Annual Meeting of the American Association for Cancer Research (AACR-2018)
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