Tezepelumab - Amgen/AstraZeneca

Drug Profile

Tezepelumab - Amgen/AstraZeneca

Alternative Names: AMG 157; MEDI-9929

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Amgen
  • Developer Amgen; AstraZeneca; Bispebjerg Hospital; Lund University; MedImmune; University of Copenhagen; University of Newcastle, Australia
  • Class Antiasthmatics; Monoclonal antibodies
  • Mechanism of Action Thymic stromal lymphopoietin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Asthma
  • Phase II Atopic dermatitis

Most Recent Events

  • 02 Mar 2018 Interim efficacy data from the phase IIb PATHWAY trial in Asthma presented at the 2018 Annual Meeting of the American Academy of Allergy, Asthma and Immunology (AAAAI-WAO-2018)
  • 22 Jan 2018 AstraZeneca in collaboration with Amgen plans the phase III SOURCE trial for Asthma (In adults, In the elderly, Treatment-experienced) in USA, Argentina, Germany, South Korea, Poland, Turkey and Ukraine (SC) in February 2018 (NCT03406078)
  • 27 Nov 2017 AstraZeneca and Amgen plan the phase III NAVIGATOR trial for Asthma (In adolescents, In adults, In the elderly) in USA, Argentina, Australia, Austria, Brazil, Canada, Germany, Japan, South Korea, Russia and Ukraine (SC) in November 2017 (NCT03347279)
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