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Lefamulin - Nabriva Therapeutics

Drug Profile

Lefamulin - Nabriva Therapeutics

Alternative Names: BC-3781; BC-3781.Ac; Lefamulin-acetate; XENLETA

Latest Information Update: 28 Nov 2019

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At a glance

  • Originator Nabriva Therapeutics
  • Class Alkenes; Antibacterials; Cyclopentanes; Diterpenes; Polycyclic compounds; Small molecules; Thioglycolates
  • Mechanism of Action Peptidyltransferase modulators; Protein 50S ribosomal subunit modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Community-acquired pneumonia
  • Phase II Skin and soft tissue infections
  • Preclinical Bacterial infections; Bone and joint infections; Nosocomial pneumonia; Osteomyelitis
  • No development reported Sexually transmitted infections

Most Recent Events

  • 28 Nov 2019 No recent reports of development identified for preclinical development in Sexually transmitted infections in USA (IV, Infusion)
  • 28 Nov 2019 No recent reports of development identified for preclinical development in Sexually transmitted infections in USA (PO, Tablet)
  • 15 Oct 2019 Pooled efficacy and safety data from the phase III LEAP 1 and LEAP 2 trials in Community-acquired pneumonia released by Nabriva Therapeutics
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