Ensituximab

Drug Profile

Ensituximab

Alternative Names: NEO-101; NEO-102; NPC-1C

Latest Information Update: 15 Jul 2017

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At a glance

  • Originator Neogenix Oncology
  • Developer Duke University Medical Center; H. Lee Moffitt Cancer Center and Research Institute; Johns Hopkins Medical Institutions; Montefiore Medical Center; National Cancer Institute (USA); Precision Biologics; University of North Carolina; University of Texas Southwestern Medical Center; Yale University School of Medicine
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Neoplasm antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Colorectal cancer; Pancreatic cancer

Most Recent Events

  • 02 Jun 2017 Efficacy and adverse events data from a phase-I/II trial in Pancreatic cancer and Colorectal cancer (Late-stage disease, Second-line therapy or greater) presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 01 Mar 2017 Precision Biologics completes a phase I/II trial in Pancreatic cancer and Colorectal cancer (Late-stage disease, Second-line therapy or greater) in USA (NCT01040000)
  • 09 Feb 2016 Updated efficacy data from a phase II trial in Colorectal cancer released by Precision Biologics
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