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Vistusertib - AstraZeneca

Drug Profile

Vistusertib - AstraZeneca

Alternative Names: AZD 2014

Latest Information Update: 17 Dec 2019

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; Cambridge University Hospitals; Massachusetts General Hospital; National Cancer Institute (USA); Netherlands Cancer Institute; NHS Greater Glasgow and Clyde; Queen Mary University of London; Samsung Medical Center; University of Birmingham; University of London; University of Texas M. D. Anderson Cancer Center
  • Class 2 ring heterocyclic compounds; Antineoplastics; Benzamides; Cytostatics; Morpholines; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action MTORC1 protein inhibitors; MTORC2 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Diffuse large B cell lymphoma; Fallopian tube cancer; Gastric cancer; Glioblastoma; Meningioma; Non-small cell lung cancer; Ovarian cancer; Peritoneal cancer; Prostate cancer; Renal cancer; Small cell lung cancer; Solid tumours

Most Recent Events

  • 08 Dec 2019 AstraZenca completes the phase-II OCTOPUS trial in Ovarian cancer (Second-line therapy or greater, Combination therapy) in United Kingdom (PO) (EudracT2014-005221-12) (ISRCTN16426935)
  • 29 Nov 2018 Discontinued - Phase-I for Prostate cancer (Early-stage disease, Neoadjuvant therapy) in United Kingdom (PO)
  • 29 Nov 2018 Discontinued - Phase-I for Solid tumours (Late-stage disease, Second-line therapy or greater) in Japan (PO)
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