Capmatinib - Novartis Oncology

Drug Profile

Capmatinib - Novartis Oncology

Alternative Names: INC-280; INCB-028060; INCB-28060

Latest Information Update: 12 Nov 2018

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At a glance

  • Originator Incyte Corporation
  • Developer Array BioPharma; Novartis Oncology
  • Class Antineoplastics; Benzamides; Heterocyclic bicyclo compounds; Imidazoles; Quinolines; Small molecules; Triazines
  • Mechanism of Action Proto oncogene protein c met inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Non-small cell lung cancer
  • Phase II Glioblastoma; Liver cancer; Malignant melanoma
  • Phase I/II Colorectal cancer; Head and neck cancer
  • Phase I Solid tumours
  • No development reported Renal cell carcinoma

Most Recent Events

  • 19 Oct 2018 Preliminary efficacy data from a phase II GEOMETRY mono-1 trial in Non-small cell lung cancer presented at the 43rd European Society for Medical Oncology Congress ESMO-2018)
  • 03 Oct 2018 Phase-II clinical trials in Non-small cell lung cancer in South Korea (PO) (NCT03693339)
  • 28 Sep 2018 No recent reports of development identified for phase-I development in Renal-cell-carcinoma(Combination therapy, Metastatic disease, Second-line therapy or greater) in USA (PO)
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