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T3D 959

Drug Profile

T3D 959

Alternative Names: DB-959; DB-959Na; T3D-959

Latest Information Update: 23 May 2025

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At a glance

  • Originator Bayer HealthCare Pharmaceuticals
  • Developer DARA BioSciences; T3D Therapeutics
  • Class Acetates; Antidementias; Antihyperglycaemics; Antihyperlipidaemics; Hepatoprotectants; Indenes; Insulin sensitisers; Oxazoles; Small molecules; Sodium compounds
  • Mechanism of Action Peroxisome proliferator-activated receptor delta agonists; Peroxisome proliferator-activated receptor gamma agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alzheimer's disease
  • No development reported Huntington's disease; Non-alcoholic fatty liver disease
  • Discontinued Dyslipidaemias; Non-alcoholic steatohepatitis; Type 2 diabetes mellitus

Most Recent Events

  • 09 May 2025 T3D Therapeutics plans a phase II/III trial for Alzheimer's Disease in USA (PO, Capsule) (NCT06964230)
  • 28 Jul 2024 Updated efficacy data from the phase II PIONEER trial in Alzheimer's disease presented at the Alzheimer's Association International Conference 2024 (AAIC-2024)
  • 28 Jul 2024 No recent reports of development identified for phase-I development in Huntington's-disease in USA (PO)

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