Drug Profile

Research programme: ERN1 protein inhibitors - MannKind Corporation

Alternative Names: Inositol requiring enzyme-1 inhibitor; IRE-1α inhibitor; MKC 204; Mkc 8866; MKC-3946

Latest Information Update: 28 Jul 2021

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At a glance

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

No development reported Multiple myeloma; Precursor cell lymphoblastic leukaemia-lymphoma

28 Jul 2021 No recent reports of development identified for preclinical development in Precursor-cell-lymphoblastic-leukaemia-lymphoma in USA
05 Dec 2020 Interim pharmacodynamics data from a preclinical study in in Precursor cell lymphoblastic leukaemia-lymphoma presented at the 62nd Annual Meeting and Exposition of the American Society of Hematology
22 Jun 2017 Preclinical trials in Acute lymphoblastic leukaemia in USA (unspecified route)

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