TG 02

Drug Profile

TG 02

Alternative Names: SB 1317; TG02

Latest Information Update: 19 Jun 2018

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At a glance

  • Originator S*BIO
  • Developer European Organisation for Research and Treatment of Cancer; National Cancer Institute (USA); S*BIO; Tragara Pharmaceuticals
  • Class Antineoplastics; Heterocyclic compounds with 4 or more rings; Small molecules
  • Mechanism of Action Cyclin-dependent kinase inhibitors; Extracellular signal-regulated MAP kinase inhibitors; Fms-like tyrosine kinase 3 inhibitors; Janus kinase-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Anaplastic astrocytoma; Glioblastoma
  • No development reported Cancer; Chronic lymphocytic leukaemia; Leukaemia; Multiple myeloma; Solid tumours

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 01 Jun 2018 Phase-I clinical trials in Anaplastic astrocytoma (In the elderly, Newly diagnosed, Combination therapy) in France, Switzerland (PO) (NCT03224104)
  • 01 Jun 2018 Phase-I clinical trials in Anaplastic astrocytoma (Monotherapy, In adults, Second-line therapy or greater) in Swaziland, France (PO) (NCT03224104)
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