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Roniciclib

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Drug Profile

Roniciclib

Alternative Names: BAY 1000394; CDK-I; Pan-CDK inhibitor

Latest Information Update: 16 Aug 2018

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At a glance

  • Originator Bayer Schering Pharma
  • Developer Bayer HealthCare Pharmaceuticals
  • Class Alcohols; Antineoplastics; Cyclopropanes; Fluorine compounds; Imines; Pyrimidines; Small molecules; Sulfones
  • Mechanism of Action Cyclin-dependent kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Small cell lung cancer; Solid tumours

Most Recent Events

  • 19 Jul 2018 Bayer completes a phase I trial in Solid tumours (Late-stage disease) in Japan (PO) (NCT02047890)
  • 01 Dec 2016 Bayer completes a phase I trial for Solid tumours in USA, France and Germany (NCT01188252)
  • 30 Jun 2016 Bayer completes a phase I clinical trial in Solid tumours (Second-line therapy or greater, Late-stage disease, Metastatic disease) in Hungary (PO) (NCT02390154)

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