PF 5057459

Drug Profile

PF 5057459

Alternative Names: CovX 241; CVX-241; PF-05057459

Latest Information Update: 26 Jan 2012

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At a glance

  • Originator CovX
  • Developer Pfizer
  • Class Antibodies; Antineoplastics; Peptides
  • Mechanism of Action Angiopoietin-2 inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 10 Nov 2011 Discontinued - Phase-I for Solid tumours in USA (IV)
  • 14 Sep 2011 Pfizer terminates phase I trial in advanced Solid tumours in USA (NCT01004822)
  • 01 Mar 2010 Phase-I clinical trials in Solid tumours in USA (IV)
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