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Ontuxizumab

Drug Profile

Ontuxizumab

Alternative Names: MORAb-004; Ontecizumab

Latest Information Update: 25 Dec 2021

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At a glance

  • Originator Ludwig Institute for Cancer Research; Morphotek
  • Developer Eisai Inc; Morphotek; National Cancer Institute (USA)
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action CD248 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Soft tissue sarcoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Colorectal cancer; Malignant melanoma; Soft tissue sarcoma
  • No development reported Lymphoma; Solid tumours

Most Recent Events

  • 25 Feb 2020 Morphotek completes a phase II trial in Malignant melanoma (Monotherapy, Metastatic disease, Second-line therapy or greater) in USA, Australia, Germany and United Kingdom (NCT01335009)
  • 28 Oct 2019 No recent reports of development identified for phase-I development in Lymphoma(In adolescents, In children, Monotherapy, Recurrent, Second-line therapy or greater) in USA (IV, Infusion)
  • 28 Oct 2019 No recent reports of development identified for phase-I development in Solid-tumours(In adolescents, In children, Monotherapy, Recurrent, Second-line therapy or greater) in USA (IV, Infusion)
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