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Rociletinib - Clovis Oncology

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Drug Profile

Rociletinib - Clovis Oncology

Alternative Names: AVL-301; CNX-419; CO-1686; EMSI programme; Xegafri

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator Avila Therapeutics
  • Developer Clovis Oncology; Genentech
  • Class Acrylamides; Antineoplastics; Pyrimidines; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Submission Withdrawal Non-small cell lung cancer

Most Recent Events

  • 20 Nov 2019 Celgene Corporation has been acquired by Bristol Myers Squibb
  • 26 Oct 2017 Pharmacodynamics data from preclinical studies presented at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC 2017 (3281193)
  • 16 May 2016 Discontinued after receiving CRL from the US FDA - Preregistration for Non-small cell lung cancer (Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (PO)

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