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Cadisegliatin - vTv Therapeutics

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Drug Profile

Cadisegliatin - vTv Therapeutics

Alternative Names: GK1-399; GKI399; TTP-399

Latest Information Update: 27 May 2025

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At a glance

  • Originator Novo Nordisk
  • Developer CinRx Pharma; vTv Therapeutics LLC
  • Class Antihyperglycaemics; Cyclohexanes; Ethers; Small molecules; Sulfhydryl compounds; Thiazoles
  • Mechanism of Action Glucokinase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Type 1 diabetes mellitus
  • Phase II Type 2 diabetes mellitus

Most Recent Events

  • 15 May 2025 vTv Therapeutics re-initiates a phase III CATT1 registrational trial for Type 1 diabetes mellitus (Adjunctive treatment) in USA (NCT06334133)
  • 17 Mar 2025 vTv Therapeutics plans to submit New Drug Application for Type I diabetes mellitus
  • 14 Mar 2025 The US FDA lifts clinical hold on the phase III CATT1 trial in type 1 diabetes mellitus

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