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Tigilanol tiglate - QBiotics

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Drug Profile

Tigilanol tiglate - QBiotics

Alternative Names: EBC 46

Latest Information Update: 13 Feb 2025

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At a glance

  • Originator QBiotics
  • Developer Cardiff University; Merck Sharp & Dohme; QBiotics; Swansea University Medical School
  • Class Antibacterials; Antineoplastics; Diterpenes; Esters; Small molecules
  • Mechanism of Action Immunostimulants; Protein kinase C stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Soft tissue sarcoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Head and neck cancer; Malignant melanoma; Soft tissue sarcoma
  • Phase I/II Solid tumours
  • No development reported Bacterial infections

Most Recent Events

  • 05 Feb 2025 Tigilanol tiglate - QBiotics receives Orphan Drug status for Soft tissue sarcoma in USA
  • 13 Sep 2024 Efficacy and adverse events data from a phase-II clinical trials in Soft tissue sarcoma presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
  • 11 Jun 2024 QBiotics completes the phase-II trial in Soft tissue sarcoma (Late-stage disease, Metastatic disease) in USA (Intratumoural)

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