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Tafasitamab - Incyte Corporation/MorphoSys

Drug Profile

Tafasitamab - Incyte Corporation/MorphoSys

Alternative Names: anti-CD19 MAb XmAb5574; anti-CD19 MoAb XmAb5574; INCMOR0208; Minjuvi; Monjuvi; MOR 208; MOR-00208; Tafasitamab-cxix; XENP-5574; XmAb-5574

Latest Information Update: 30 Dec 2021

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At a glance

  • Originator Xencor
  • Developer Incyte Corporation; MorphoSys; University Medical Center of the Johannes Gutenberg University Mainz; Xencor
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Diffuse large B cell lymphoma
  • Phase III Follicular lymphoma; Marginal zone B-cell lymphoma
  • Phase II B-cell lymphoma; Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 01 Dec 2021 MorphoSys completes phase II trial for Chronic lymphocytic leukaemia (Combination therapy, Second-line therapy or greater) in Austria, France, Italy, Germany, Poland, United Kingdom and USA (IV) (NCT02639910)
  • 02 Nov 2021 Incyte Corporation plans phase II coreMIND trial for Chronic lymphocytic leukaemia (Second-line therapy or greater) in USA
  • 21 Oct 2021 Tafasitamab licensed to Specialised Therapeutics Asia in Australia, New Zealand and Singapore
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