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Tafasitamab - Incyte Corporation

Drug Profile

Tafasitamab - Incyte Corporation

Alternative Names: anti-CD19 MAb XmAb5574; anti-CD19 MoAb XmAb5574; ICP-B04; INCMOR0208; Minjuvi; Monjuvi; MOR 208; MOR-00208; Tafasitamab-cxix; XENP-5574; XmAb-5574

Latest Information Update: 06 Mar 2024

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At a glance

  • Originator Xencor
  • Developer Incyte Corporation; InnoCare Pharma; Knight Therapeutics; MorphoSys; Pfizer; University Medical Center of the Johannes Gutenberg University Mainz; Xencor
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Diffuse large B cell lymphoma
  • Phase III Follicular lymphoma; Marginal zone B-cell lymphoma
  • Phase II B-cell lymphoma; Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma

Most Recent Events

  • 29 Feb 2024 Launched for Diffuse large B cell lymphoma (Combination therapy, Second-line therapy or greater) in Brazil (IV)
  • 05 Feb 2024 Incyte enters asset purchase agreement with MorphoSys for Tafasitamab Worldwide
  • 22 Jan 2024 Medical Products Administration of Guangdong Province approves afasitamab (Minjuvi®) in combination with lenalidomide under early access programme for Diffuse large B-cell lymphoma in Hong Kong and Macao
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