Angiotensin-1-7

Drug Profile

Angiotensin-1-7

Alternative Names: TXA 127

Latest Information Update: 03 Apr 2018

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At a glance

  • Originator Tarix Orphan; Tarix Pharmaceuticals
  • Developer Constant Pharmaceuticals; Tarix Pharmaceuticals; Unigene Laboratories; US Biotest Inc
  • Class Antihypertensives; Heart failure therapies; Peptide hormones
  • Mechanism of Action
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Epidermolysis bullosa; Muscular dystrophies; Duchenne muscular dystrophy; Myelodysplastic syndromes; Pulmonary arterial hypertension; Limb girdle muscular dystrophies; Stem cell engraftment
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Amyotrophic lateral sclerosis; Connective tissue disorders; Duchenne muscular dystrophy; Epidermolysis bullosa; Limb girdle muscular dystrophies; Muscular dystrophies; Stroke
  • Discontinued Adult respiratory distress syndrome; HIV infections; Peripheral vascular disorders; Pulmonary arterial hypertension; Stem cell engraftment; Thrombocytopenia

Most Recent Events

  • 27 Mar 2018 Constant Pharmaceuticals will receive patent allowance for Angiotensin-1-7 in the European Union
  • 27 Mar 2018 Constant Pharmaceuticals plans a phase II trial for stroke recovery in the early 2019
  • 12 Jun 2017 Angiotensin-1-7 receives Orphan Drug status for Epidermolysis bullosa in European Union
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