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F8 IL10

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Drug Profile

F8 IL10

Alternative Names: Dekavil; F8-IL10; PF 06687234

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Philogen
  • Developer Pfizer; Philogen
  • Class Anti-inflammatories; Antirheumatics; Cytokines; Monoclonal antibodies; Recombinant fusion proteins
  • Mechanism of Action Interleukin 10 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Inflammation; Rheumatoid arthritis
  • Discontinued Ulcerative colitis

Most Recent Events

  • 08 Jun 2023 Philogen terminates a phase II trial in Rheumatoid arthritis (Combination therapy) in Italy, Germany, Switzerland (SC), due to the approvals of new agents for the same indication have significantly slowed down the recruitment in this trial making the prosecution of the present investigation extremely difficult (NCT02270632)
  • 18 Nov 2022 Philogen plans a phase I trial for Rheumatoid arthritis (In adults, In the elderly) in March 2023 (intra-articular)(NCT05622175)
  • 24 Dec 2021 Phase-II clinical trials in Inflammation in Italy (IV) (Philogen pipeline, December 2021)

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