Imeglimin - Poxel

Drug Profile

Imeglimin - Poxel

Alternative Names: EMD-387008; PXL 008; RVT-1501

Latest Information Update: 12 Oct 2018

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At a glance

  • Originator Merck KGaA
  • Developer Poxel
  • Class Amines; Antihyperglycaemics; Small molecules; Triazines
  • Mechanism of Action AMP activated protein kinase stimulants; Glucose modulators; Mitochondrial permeability transition pore inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Type 2 diabetes mellitus

Most Recent Events

  • 08 Oct 2018 Poxel completes enrolment in the TIMES 2 phase III trial for Type-2 diabetes mellitus in Japan
  • 26 Sep 2018 Poxel prematurely terminated a phase IIa trial in Type-2 diabetes mellitus (In volunteers) in Germany (EudraCT2016-003215-35)
  • 30 Aug 2018 Imeglimin - Poxel is available for licensing as of 30 Aug 2018.
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