Imeglimin - Poxel

Drug Profile

Imeglimin - Poxel

Alternative Names: EMD-387008; PXL 008; RVT-1501

Latest Information Update: 16 Feb 2018

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At a glance

  • Originator Merck KGaA
  • Developer Poxel
  • Class Amines; Antihyperglycaemics; Small molecules; Triazines
  • Mechanism of Action AMP activated protein kinase stimulants; Glucose modulators; Mitochondrial permeability transition pore inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Type 2 diabetes mellitus

Most Recent Events

  • 12 Feb 2018 Poxel plans a phase III trials for Type-2 diabetes mellitus in USA and Europe in 2019
  • 12 Feb 2018 Poxel and Roivant Sciences agree to co-promote and co-develop imeglimin in USA, Europe and World for type-2 diabetes mellitus
  • 22 Jan 2018 Poxel announces intention to submit NDA to the Pharmaceuticals and Medical Devices Agency for Type-2 diabetes mellitus in Japan in 2020
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