Imeglimin - Poxel

Drug Profile

Imeglimin - Poxel

Alternative Names: EMD-387008; PXL 008; RVT-1501

Latest Information Update: 06 Jul 2018

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At a glance

  • Originator Merck KGaA
  • Developer Poxel
  • Class Amines; Antihyperglycaemics; Small molecules; Triazines
  • Mechanism of Action AMP activated protein kinase stimulants; Glucose modulators; Mitochondrial permeability transition pore inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Type 2 diabetes mellitus

Most Recent Events

  • 03 Jul 2018 Poxel completes enrolment in the TIMES 1 phase III trial for Type-2 Diabetes in Japan
  • 25 Jun 2018 Pharmacodynamics data from a preclinical study in Type-2 diabetes mellitus presented at the 78th Annual Scientific Sessions of the American Diabetes Association (ADA-2018)
  • 28 Mar 2018 No recent reports of development identified for phase-I development in Type-2-diabetes-mellitus in United Kingdom (PO, Tablet)
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