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Idroxioleic acid - Laminar Pharmaceuticals

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Drug Profile

Idroxioleic acid - Laminar Pharmaceuticals

Alternative Names: 2-hydroxy-9-cis octadecenoic - Laminar Pharmaceuticals; 2-Hydroxyoleic acid - Laminar Pharmaceuticals; 2-OHOA - Laminar Pharmaceuticals; LAM-561; LP561A1; Minerval

Latest Information Update: 14 Jun 2024

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At a glance

  • Originator University of the Balearic Islands
  • Developer Dana-Farber Cancer Institute; Hackensack Meridian Health; Laminar Pharmaceuticals
  • Class Anorectics; Antineoplastics; Oleic acids
  • Mechanism of Action Furin inhibitors; Notch signalling pathway inhibitors; Phosphatidylcholine ceramide phosphocholine transferase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Glioblastoma
  • Phase I/II Glioma; Solid tumours

Most Recent Events

  • 11 Jun 2024 Laminar Pharmaceuticals announces intention to submit regulatory filings for full marketing authorization to EMA for Glioblastoma in 2026
  • 11 Jun 2024 Laminar Pharmaceuticals announces intention to submit regulatory filings or conditional marketing authorization to EMA for Glioblastoma in early 2025
  • 11 Jun 2024 Laminar Pharmaceuticals completes enrolment in the phase IIb/III CLINGLIO trial for Glioblastoma in Spain, Israel, Italy, France and United Kingdom (NCT04250922)

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