Remetinostat - Medivir AB
Alternative Names: Remetinostat gel 1%; SHAPE; SHP-141; SHP-141C; Suberohydroxamic acid phenyl esterLatest Information Update: 29 Nov 2021
At a glance
- Originator Dana-Farber Cancer Institute; Harvard University
- Developer Medivir AB; Shape Pharmaceuticals; Stanford University School of Medicine
- Class Antineoplastics; Antipsoriatics; Benzoic acids; Small molecules
- Mechanism of Action Histone deacetylase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes - Basal cell cancer; Cutaneous T-cell lymphoma
Highest Development Phases
- Phase II Basal cell cancer; Cutaneous T-cell lymphoma; Squamous cell cancer
- Discontinued Plaque psoriasis
Most Recent Events
- 18 Nov 2021 Updated efficacy data from a phase II trial in Squamous cell cancer was released by Medivir
- 16 Aug 2021 Medivir AB restructures agreement with TetraLogic Pharmaceuticals Corporation and The Leukemia & Lymphoma Society for remetinostat in the treatment of cutaneous T-cell lymphoma and other types of skin cancers
- 12 Aug 2021 Efficacy and safety data from phase II trial in Basal cell cancer released by Medivir