Tesidolumab - MorphoSys/Novartis

Drug Profile

Tesidolumab - MorphoSys/Novartis

Alternative Names: LFG-316; NOV-4

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator MorphoSys; Novartis
  • Class Eye disorder therapies; Monoclonal antibodies
  • Mechanism of Action Complement C5 inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Choroiditis; Dry age-related macular degeneration; Panuveitis; Paroxysmal nocturnal haemoglobinuria; Thrombotic microangiopathy; Wet age-related macular degeneration

Most Recent Events

  • 01 Dec 2017 Alcon Research completes a phase II trial for Dry age-related macular degeneration (Combination therapy) in USA (Intravitreal) (NCT02515942)
  • 28 Sep 2017 Novartis terminates a phase II trial in Thrombotic microangiopathy (In adolescents, In children, In adults) in United Kingdom, Germany, France, USA (IV) (EudraCT2014-004972-49) (NCT02763644)
  • 24 Aug 2017 Novartis completes a phase II trial for Multifocal choroiditis & Panuveitis in United Kingdom and USA (Intravitreous) (NCT01526889)
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