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Tesidolumab - MorphoSys

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Drug Profile

Tesidolumab - MorphoSys

Alternative Names: LFG-316; NOV-4

Latest Information Update: 25 Jul 2024

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At a glance

  • Originator MorphoSys; Novartis
  • Class Eye disorder therapies; Monoclonal antibodies
  • Mechanism of Action Complement C5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Paroxysmal nocturnal haemoglobinuria
  • Discontinued Choroiditis; Dry age-related macular degeneration; Panuveitis; Thrombotic microangiopathy; Wet age-related macular degeneration

Most Recent Events

  • 02 Jun 2023 Adverse events and efficacy data from a phase II trial in Paroxysmal nocturnal haemoglobinuria presented at the 28th Congress of the European Haematology Association (EHA-2023)
  • 24 May 2022 Novartis completes a phase II trial in Paroxysmal nocturnal haemoglobinuria in Japan, Lithuania and Czech Republic (IV) (NCT02534909)
  • 08 Sep 2021 Tesidolumab is still in phase-II clinical trials in Paroxysmal nocturnal haemoglobinuria in Lithuania, Japan and Czech Republic (IV)

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