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N 6022

Drug Profile

N 6022

Alternative Names: N6022

Latest Information Update: 26 Jul 2017

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At a glance

  • Originator NitroMed
  • Developer Nivalis Therapeutics
  • Class Amides; Anti-inflammatories; Antiasthmatics; Carboxylic acids; Pyrroles; Small molecules
  • Mechanism of Action Alcohol dehydrogenase inhibitors; Glutathione-independent formaldehyde dehydrogenase inhibitors; Nitric oxide stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Acute asthma; Asthma; Chronic obstructive pulmonary disease; Inflammatory bowel diseases
  • Discontinued Cystic fibrosis

Most Recent Events

  • 25 Jul 2017 Alpine Immune Sciences has merged with Nivalis Therapeutics forming Alpine Immune Sciences
  • 31 May 2014 N30 Pharmaceuticals completes a phase Ib trial in Cystic fibrosis in USA (NCT01746784)
  • 20 Mar 2013 Preclinical pharmacodynamics data from a mouse model of asthma released by N30 Pharma
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