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Research programme: stapled peptide therapeutics - Rein Therapeutics/Roche

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Drug Profile

Research programme: stapled peptide therapeutics - Rein Therapeutics/Roche

Alternative Names: ATSP-7041; MDM2/MDMX dual inhibitor for p53-dependent cancers - Rein Therapeutics/Roche

Latest Information Update: 21 Jan 2025

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At a glance

  • Originator Aileron Therapeutics; Roche
  • Developer Rein Therapeutics; Roche
  • Class Peptides
  • Mechanism of Action Protein modulators; Proto-oncogene protein c-mdm2 inhibitors; Tumour suppressor protein p53 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported CNS disorders; Haematological malignancies; Inflammation; Metabolic disorders; Solid tumours; Viral infections

Most Recent Events

  • 10 Jan 2025 Aileron Therapeutics is now called Rein Therapeutics
  • 28 Jul 2018 No recent reports of development identified for preclinical development in Haematological-malignancies in USA (IV)
  • 16 Jul 2016 No recent reports of development identified for preclinical development in CNS-disorders in USA

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