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Tefinostat - Chroma Therapeutics

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Drug Profile

Tefinostat - Chroma Therapeutics

Alternative Names: CHR-2845; Tefinostat tartrate

Latest Information Update: 08 Sep 2021

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At a glance

  • Originator Chroma Therapeutics
  • Developer Cardiff University; Chroma Therapeutics
  • Class Antineoplastics; Esters; Small molecules
  • Mechanism of Action Histone deacetylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Inflammation
  • No development reported Chronic myelomonocytic leukaemia; Haematological malignancies; Lymphoma

Most Recent Events

  • 08 Sep 2021 No development reported - Phase-II for Chronic myelomonocytic leukaemia in United Kingdom (PO)
  • 26 Jul 2019 Cardiff University completes the phase II MONOCLE trial in Chronic myelomonocytic leukaemia in United Kingdom (PO) (ISRCTN17394489) (EudraCT2015-002281-23)
  • 01 Dec 2018 Efficacy and adverse events data from a phase II trial in Chronic myelomonocytic leukaemia presented at the 60th Annual Meeting and Exposition of the American Society of Haematology (ASH-Hem-2018)

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