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Pemafibrate - Kowa Pharmaceutical

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Drug Profile

Pemafibrate - Kowa Pharmaceutical

Alternative Names: K 877; K-808; K-877 CR; K-877 IR; K-877-BC; K-877-ER; K-877-FL; Parmodia

Latest Information Update: 14 Aug 2024

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At a glance

  • Originator Kowa Pharmaceutical
  • Developer Jaeb Center for Health Research; Kowa Pharmaceutical
  • Class Antihyperlipidaemics; Benzoxazoles; Butyric acids; Eye disorder therapies; Fibric acid derivatives; Hepatoprotectants; Small molecules
  • Mechanism of Action Peroxisome proliferator-activated receptor alpha agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hyperlipidaemia
  • Preregistration Dyslipidaemias
  • Phase III Diabetic retinopathy; Hypercholesterolaemia; Hypertriglyceridaemia
  • Phase II Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Primary biliary cirrhosis

Most Recent Events

  • 14 Aug 2024 Kowa Research Institute plans a phase I trial for in Primary biliary cirrhosis in August 2024 (NCT06525311)
  • 26 Jan 2024 Phase-II clinical trials in Primary biliary cirrhosis (Treatment-experienced) in USA (PO) (NCT06247735) .
  • 01 Oct 2023 Phase-II clinical trials in Primary biliary cirrhosis in Japan (PO) (Kowa Pharmaceuticals pipeline, October 2023)

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