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Zamicastat - Bial

Drug Profile

Zamicastat - Bial

Alternative Names: BIA-5-1058

Latest Information Update: 13 Nov 2019

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At a glance

  • Originator Bial
  • Developer BIAL
  • Class Antihypertensives; Chromans; Heart failure therapies; Imidazoles; Small molecules; Thiones
  • Mechanism of Action Dopamine beta hydroxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Pulmonary arterial hypertension
  • Phase I Heart failure

Most Recent Events

  • 23 Aug 2019 Bial initiates completes enrolment in a phase I trial in healthy volunteers in United Kingdom before August 2019(NCT04069130)
  • 08 Apr 2019 Bial initiates a phase I trial in healthy volunteers in United Kingdom (NCT04069130)
  • 20 Dec 2018 Phase-II clinical trials in Pulmonary arterial hypertension (Adjuvant therapy) in Austria (PO) (EudraCT2018-002796-18 )
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