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Alternative Names:
Alpericive - Novartis Oncology; BYL-719; NVP-BYL-719; Piqray
Latest Information Update: 13 Oct 2021
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At a glance
Originator
Novartis
Developer
Columbia University; H. Lee Moffitt Cancer Center and Research Institute; Memorial Sloan-Kettering Cancer Center; Novartis; Novartis Oncology; University Health Network
Class
Amides; Antineoplastics; Fluorine compounds; Pyridines; Pyrrolidines; Small molecules; Thiazoles
Mechanism of Action
Phosphatidylinositol 3 kinase alpha inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
27 Sep 2021
Phase-III clinical trials in Breast cancer (Second-line therapy or greater, Combination therapy, Metastatic disease) in Germany, Hungary (PO) (NCT05038735) (EudraCT2021-001966-39)
09 Sep 2021
Novartis Pharmaceuticals plans the phase III EPIK-B5 trial for Breast Cancer (Combination therapy, Late-stage disease, Second-line therapy or greater) in October 2021 (PO) (NCT05038735)
28 Jul 2021
Novartis plans the phase II EPIK-3 trial in Growth disorders (In adults, In adolescents, In children, In elderly) in September 2021 (NCT04980833)
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