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Vosoritide - BioMarin Pharmaceutical

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Drug Profile

Vosoritide - BioMarin Pharmaceutical

Alternative Names: BMN-111; Modified C-natriuretic peptide - BioMarin Pharmaceutical; Modified recombinant human C-type natriuretic peptide - BioMarin Pharmaceutical; ProCNP38; VOXZOGO

Latest Information Update: 20 Jun 2024

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At a glance

  • Originator BioMarin Pharmaceutical
  • Class Cyclic peptides; Natriuretic agents; Natriuretic peptides; Recombinant proteins
  • Mechanism of Action Atrial natriuretic factor receptor B agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Achondroplasia; Hypochondroplasia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Achondroplasia
  • Phase II Short stature

Most Recent Events

  • 17 Jun 2024 Efficacy data from the phase II 111-205 trial in Achondroplasia was released by BioMarin
  • 17 Jun 2024 BioMarin Pharmaceutical plans multiple clinical trials in Turner's syndrome and Noonan syndrome later this year
  • 29 Apr 2024 BioMarin plans a phase II trial for Short stature (In children) in September 2024 (Injection) (NCT06382155)

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