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Vosoritide - BioMarin Pharmaceutical

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Drug Profile

Vosoritide - BioMarin Pharmaceutical

Alternative Names: BMN-111; Modified C-natriuretic peptide - BioMarin Pharmaceutical; Modified recombinant human C-type natriuretic peptide - BioMarin Pharmaceutical; ProCNP38; VOXZOGO

Latest Information Update: 11 May 2025

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At a glance

  • Originator BioMarin Pharmaceutical
  • Class Cyclic peptides; Natriuretic agents; Natriuretic peptides; Recombinant proteins
  • Mechanism of Action Atrial natriuretic factor receptor B agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Achondroplasia; Hypochondroplasia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Achondroplasia
  • Phase III Hypochondroplasia
  • Phase II Noonan syndrome; Short stature; Turner's syndrome

Most Recent Events

  • 01 May 2025 BioMarin announces intention to launch Vosoritide for Hypochondroplasia in 2027
  • 31 Dec 2024 BioMarin Pharmaceutical has patent protection for Vosoritide in European Union
  • 24 Nov 2024 Phase-II clinical trials in Short stature (Treatment-experienced, In children) in France, USA (unspecified route) (NCT06668805)

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