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RNS 60

Drug Profile

RNS 60

Alternative Names: Oxygenated saline; RNS60

Latest Information Update: 10 Dec 2021

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At a glance

  • Originator Revalesio
  • Developer Revalesio; Rush University
  • Class Anti-ischaemics; Antiasthmatics; Antidementias; Antiparkinsonians; Neuroprotectants; Vascular disorder therapies
  • Mechanism of Action G protein-coupled receptor modulators; HSP90 heat-shock protein modulators; Ion channel modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Asthma; Multiple sclerosis; Stroke
  • No development reported Alzheimer's disease; Myocardial infarction; Parkinson's disease

Most Recent Events

  • 07 Dec 2021 Efficacy and adverse events data from a phase II trial in Amyotrophic lateral sclerosis presented at the 32nd International Symposium on ALS/MND
  • 08 Nov 2021 Revalesio Corporation, Mario Negri Institute for Pharmacological Research, ALS Association and Get out ONLUS completes a phase II trial in Amyotrophic lateral sclerosis (In adults, In the elderly) in Italy and USA (IV, Inhalation) (NCT03456882) (EudraCT2016-002382-62)
  • 07 Jul 2021 Phase-II clinical trials in Stroke (In adults, In the elderly) in USA (Injection) (NCT04693715)
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